Adults with insomnia are treated with zopiclone for a short period of time (7–14 days). It is used to treat individuals with sleep issues, including:

Having trouble falling asleep

In the middle of the night, waking up

Getting up too early

severe or distressing sleep issues brought on by emotional or mental health issues

Long-term (more than 4 week) usage of blue zopiclone for chronic insomnia is not advised since it may result in tolerance and dependency, which might induce withdrawal and rebound insomnia if suddenly stopped. Long-term usage of a medicine is typically regarded as "off-label" or an unauthorised application.

The usage of this drug raises the risk of misuse, physical dependency, and/or psychological dependence. The risk of dependency increases with dosage and treatment time and is higher in individuals with a history of mental illnesses and/or alcohol, illicit drug, or drug misuse, as well as when this medicine is used for more than 4 weeks.